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Anticoagulants: Phenobarbital lowers the plasma amounts of dicumarol (name Formerly utilised: bishydroxycoumarin) and results in a reduce in anticoagulant action as measured with the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing amplified metabolism and lessened anticoagulant reaction of oral anticoagulants (e.pentoba

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